Most of the film was shot in Los Angeles, California, including scenes set in Tijuana, while scenes set on the Mexican border were actually filmed at the border in Yuma, Arizona. It is Cheech & Chong's first feature-length film.Ĭheech & Chong had been a counterculture comedy team for about ten years before they started reworking some of their material for their first film. Up in Smoke (also referred to as Cheech & Chong's Up in Smoke) is a 1978 American comedy film directed by Lou Adler and starring Cheech Marin, Tommy Chong, Edie Adams, Strother Martin, Stacy Keach, and Tom Skerritt.